CJC-1295 No DAC + Ipamorelin
This blend combines two complementary peptides: a Growth Hormone Releasing Hormone (GHRH) analogue and a Growth Hormone Secretagogue (GHS).
CJC-1295 No DAC is a synthetic analogue of GHRH that triggers the anterior pituitary gland to release growth hormone (GH) in rhythmic pulses, closely mirroring the body’s natural secretion cycle.
Ipamorelin, a highly selective ghrelin receptor agonist, works through a different pathway to further increase GH output without significantly affecting cortisol or prolactin levels. When paired together, the two peptides create a synergistic amplification of GH pulses, enhancing both metabolic and regenerative outcomes.
Key Benefits
- Promotes lipolysis, accelerating the breakdown of stored fat
- Supports lean muscle preservation and development
- Stimulates tissue regeneration in muscles, tendons, and ligaments
- Enhances recovery from exercise and microtrauma
- Increases collagen production, improving skin tone and elasticity
- Provides anti-aging and cosmetic rejuvenation potential through GH modulation
- Linked to better sleep quality and deeper rest cycles
- May elevate energy levels, mood, and recovery from fatigue
CJC-1295 vs. CJC-1295 No DAC
CJC-1295 with DAC (Drug Affinity Complex) includes an added molecular component that allows it to bind to albumin in the bloodstream, giving it an extended half-life of 6–8 days. This provides prolonged GH and IGF-1 elevation from a single injection. However, because GH remains continuously elevated, it carries a higher risk of receptor desensitization over time.
In contrast, CJC-1295 No DAC lacks this attachment, giving it a much shorter half-life of approximately 30 minutes, with biological activity lasting 2–3 hours. This version is typically administered 2–3 times daily to mimic the natural pulsatile release of growth hormone, reducing the likelihood of desensitization and promoting more physiologic GH signaling.
Stacking & Synergistic Pairings
- L-Carnitine – Supports fatty acid transport and oxidation, aiding body recomposition
- AOD-9604 – Boosts lipolysis and fat loss without affecting blood glucose
- BPC-157 or TB-500 – Accelerate soft tissue, tendon, and joint recovery in synergy with GH-driven repair
